Atomic resolution cryo-EM instrument with enhanced productivity and compact design.

The new award-winning Thermo Scientific Krios G4 Cryo-Transmission Electron Microscope (Cryo-TEM) enables you to unravel life at the molecular level—easier, faster, and more reliably than ever before. The most compact TEM in its class, the Krios G4 Cryo-TEM consists of a highly stable 300 kV TEM platform and the industry-leading Autoloader (a cryogenic sample manipulation robot), making it ideally suited for automated applications such as single-particle analysis (SPA)cryo-electron tomography (cryo-ET) and micro-electron diffraction (microED).

Through a thorough redesign of the mechanical base frame and system enclosure, the microscope height has been reduced to below 3 m, which allows for instrument installation in labs with a ceiling height below 3.04 m (~10 ft), preventing costly room renovations. Built-in connectivity ensures a robust and risk-free pathway throughout the entire workflow, from sample preparation and optimization to image acquisition and data processing.