TEM and STEM analysis for high contrast imaging of beam sensitive materials.

The Thermo Scientific Talos F200C (S)TEM is a 20-200 kV thermionic (scanning) transmission electron microscope uniquely designed for performance and productivity across a wide range of samples and applications, such as 2D and 3D imaging of cells, organelles, asbestos, polymers, and soft materials, both at ambient and cryogenic temperatures.

It elevates the imaging quality of beam-sensitive materials with its optional, motorized, retractable cryo-box and low-dose technique. Additionally, a side-entry retractable energy dispersive spectroscopy (EDS) detector can be added to the configuration to enable chemical analysis. The large C-Twin pole piece gap, which provides high application flexibility, combined with a reproducibly performing electron column, opens new opportunities for high-resolution 3D characterization, in situ dynamic observations, and diffraction applications, with a special emphasis on high-contrast imaging and cryo-TEM. The Talos F200C (S)TEM is equipped with the fast 4k × 4k Thermo Scientific Ceta 16M Camera, which provides a large field-of-view and fast imaging, with high sensitivity, on a 64-bit platform.

Thermo Scientific Maps Software enables intuitive image-based navigation over a whole sample and easy correlation of results across imaging platforms. In order to retrieve large-area imaging at high-resolution Maps Software automatically acquires and stitches images to document the entire area of interest with exceptional quality. Maps Software can be used across tools and within the tool. It supports image import, overlay and alignment from other microscopes, such as SEM and light microscopy. This enables digital zoom from correlated low-magnification TEM and/or SEM to high-resolution TEM (HRTEM), which provides valuable contextual information.